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Abstract
After treatment of chronic hepatitis C with protease inhibitors such as telaprevir and boceprevir, increased sustained virologic response rates have been achieved compared to interferon and ribavirin. However, serious adverse effects were increased due to these agents as well. One of the important adverse effects related to telaprevir is skin rash. A case of chronic hepatitis C with telaprevir-associated rash succesfully treated by switching to boceprevir was presented. Klimik Dergisi 2017; 30(1): 36-7.