Early Release

Early Release / Review Article

Prof. Dr. Abdülkadir Noyan: Professional and Academic Aspects

Turhan Ada

Most Read

  1. Pneumococcal Vaccine as One of the Immunization Coverage Targets for Adulthood Vaccines: A Consensus Report of the Study Group for Adult Immunization of the Turkish Society of Clinical Microbiology and Infectious Diseases
  2. Does Hepatitis B Affect Erectile Dysfunction and Lower Urinary Tract Symptoms?
  3. HIV Infection in Turkey: How Close Are We to the Target?
  4. Evaluation of HBeAg-Negative Chronic Hepatitis B Patients Who Had Undergone Liver Biopsy in Accordance With the Guidelines
  5. Diagnosis, Treatment and Prevention of Diabetic Foot Wounds and Infections: Turkish Consensus Report
  6. When to Stop Antiviral Therapy in Chronic Hepatitis B
  7. Mycoplasma hominis and Ureaplasma urealyticum: Their Role in Urogenital System Infections and Retrospective Evaluation of Antibiotic Resistance Rates
  8. Crimean-Congo Haemorrhagic Fever: Treatment and Use of Ribavirin
  9. Modern Diagnostic Methods Used in Bacteriology: Rapid and Effective
  10. Analysis of HIV/AIDS-Related Stigma and Discrimination in Turkey: Results of the People Living With HIV Stigma Index

Volume 35, Issue 2

Original Article

Evaluation of the Distribution and Antibiotic Resistance Profile of Strains Isolated from Urine Specimens

Havva Avcıküçük
Affiliations
  • 29 Mayıs Devlet Hastanesi, Tıbbi Mikrobiyoloji Kliniği, Ankara, Türkiye
https://orcid.org/0000-0003-4808-7312
,
Nilgün Altın
Affiliations
  • Sağlık Bilimleri Üniversitesi Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Kliniği, Ankara, Türkiye
https://orcid.org/0000-0002-6211-712X
  • antimicrobial resistance
  • empiric treatment
  • urinary tract infection

Abstract

Objective: Urinary tract infections (UTI) are the most common among the community and hospital-acquired infections. Escherichia coli is the most frequently isolated microorganism in UTIs. The treatment is mostly empirical. However, resistance related to the inappropriate use of antibiotics causes problems. Therefore, determining regional antibiotic resistance profiles and regular surveillance is essential. Therefore, we aimed to evaluate the distribution of strains and their resistance patterns isolated from urine samples at our laboratory. 

Methods: The results of urine samples sent to our laboratory between January 1, 2018, and December 31, 2018, were analyzed retrospectively. Conventional methods and the automatized device performed identification and antimicrobial susceptibility of the isolates. 

Results: Significant bacterial growth was detected in 2331(14.1%) of 16 521 urine samples, and 2051 were included in the study. The most frequently isolated strain was E. coli (70.4%). The resistance rate was highest for ampicillin (61.4%) among the bacteria that belong to the Enterobacteriaceae family. The most susceptible antibiotics were fosfomycin, imipenem, and meropenem, respectively. Pseudomonas aeruginosa and Acinetobacter spp. were found to have multidrug resistance. ESBL positivity was 19.3%. Among ESBL positive strains, the highest resistance rates were against ampicillin (98.2%). All the Enterococcus spp. isolates were susceptible to linezolid. All the S. saprophyticus isolates were susceptible to ciprofloxacin, linezolid, vancomycin, teicoplanin, and trimethoprim-sulfamethoxazole. All S. agalactiae strains were susceptible to penicillin, vancomycin, teicoplanin, and linezolid.

Conclusion: Pathogens responsible for urinary tract infections and antibiotic resistance rates differ among inpatients and outpatients. Therefore, it is essential to identify UTI agents, perform antibiotic susceptibility tests, and conduct surveillance studies at hospitals and regional levels to guide successful empirical treatment of in-and-outpatients.

  • 95-102
  • Nilgün Altın
  • [email protected]
  • 10.36519/kd.2022.3974
  • August 10, 2021
  • March 6, 2022
  • June 27, 2022

  • Avcıküçük H, Altın N. [Evaluation of the distribution and antibiotic resistance profile of strains isolated from urine specimens]. Klimik Derg. 2022;35(2):95-102. Turkish.
  • 551
  • 331
Download as PDF
  • This work is licensed under a Creative Commons Attribution-Non Commercial 4.0 International License. CC BY-NC
Volume 37, Issue 3 Volume 37, Issue 2 Volume 37, Issue 1 Volume 36, Issue 4 Volume 36, Supplement 1 Volume 36, Issue 3 Volume 36, Issue 2 Volume 36, Issue 1 Volume 35, Issue 4 Volume 35, Issue 3 Volume 35, Issue 2 Volume 35, Issue 1 Volume 34, Issue 3 Volume 34, Issue 2 Volume 34, Issue 1 Volume 33, Issue 3 Volume 33, Issue 2 Volume 33, Issue 1 Volume 32, Issue 3 Volume 32, Supplement 1 Volume 32, Supplement 2 Volume 32, Issue 2 Volume 32, Issue 1 Volume 31, Issue 3 Volume 31, Issue 2 Volume 31, Supplement 1 Volume 31, Issue 1 Volume 30, Issue 3 Volume 30, Issue 2 Volume 30, Supplement 1 Volume 30, Issue 1 Volume 29, Issue 3 Volume 29, Issue 2 Volume 29, Issue 1 Volume 28, Supplement 1 Volume 28, Issue 3 Volume 28, Issue 2 Volume 28, Issue 1 Volume 27, Supplement 1 Volume 27, Issue 3 Volume 27, Issue 2 Volume 27, Issue 1 Volume 26, Issue 3 Volume 26, Supplement 1 Volume 26, Issue 2 Volume 26, Issue 1 Volume 25, Issue 3 Volume 25, Issue 2 Volume 25, Issue 1 Volume 24, Issue 3 Volume 24, Issue 2 Volume 24, Issue 1 Volume 23, Issue 3 Volume 23, Issue 2 Volume 23, Issue 1 Volume 22, Issue 3 Volume 22, Issue 2 Volume 22, Issue 1 Volume 21, Issue 3 Volume 21, Supplement 2 Volume 21, Supplement 1 Volume 21, Issue 2 Volume 21, Issue 1 Volume 20, Issue 3 Volume 20, Supplement 2 Volume 20, Issue 2 Volume 20, Issue 1 Volume 20, Supplement 1 Volume 19, Issue 3 Volume 19, Issue 2 Volume 19, Issue 1 Volume 18, Issue 3 Volume 18, Supplement 1 Volume 18, Issue 2 Volume 18, Issue 1 Volume 17, Issue 3 Volume 17, Issue 2 Volume 17, Issue 1 Volume 16, Issue 3 Volume 16, Issue 2 Volume 16, Issue 1 Volume 1, Supplement 1 Volume 15, Issue 3 Volume 15, Issue 2 Volume 15, Issue 1 Volume 14, Issue 3 Volume 14, Issue 2 Volume 14, Issue 1 Volume 13, Issue 3 Volume 13, Issue 2 Volume 13, Supplement 1 Volume 13, Issue 1 Volume 12, Issue 3 Volume 12, Issue 2 Volume 12, Issue 1 Volume 11, Issue 3 Volume 11, Issue 2 Volume 11, Supplement 1 Volume 11, Issue 1 Volume 10, Issue 3 Volume 10, Issue 2 Volume 10, Issue 1 Volume 9, Issue 3 Volume 9, Issue 2 Volume 9, Issue 1 Volume 8, Issue 3 Volume 8, Issue 2 Volume 8, Issue 1 Volume 6, Issue 3 Volume 7, Issue 1 Volume 7, Issue 2 Volume 7, Issue 3 Volume 4, Issue 3 Volume 5, Issue 1 Volume 5, Issue 2 Volume 5, Issue 3 Volume 6, Issue 1 Volume 6, Issue 2 Volume 3, Issue 1 Volume 3, Issue 2 Volume 3, Issue 3 Volume 4, Issue 1 Volume 4, Issue 2 Volume 1, Issue 2 Volume 2, Issue 1 Volume 2, Issue 2 Volume 2, Issue 3 Volume 1, Issue 1