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Abstract
Infective endocarditis (IE) is a rare and highly mortal infectious disease. A 41-year-old male patient who was being followed with the diagnosis of acute coronary syndrome, acute cerebrovascular disease, meningitis and sepsis, was diagnosed with IE with the presence of vegetation on the mitral valve and Staphylococcus aureus growth in his blood culture. The patient was treated with cefazolin plus vancomycin. We present this case to remind that IE can cause various complications and careful examination may be required for the diagnosis.