Most Read

  1. Pneumococcal Vaccine as One of the Immunization Coverage Targets for Adulthood Vaccines: A Consensus Report of the Study Group for Adult Immunization of the Turkish Society of Clinical Microbiology and Infectious Diseases
  2. Does Hepatitis B Affect Erectile Dysfunction and Lower Urinary Tract Symptoms?
  3. HIV Infection in Turkey: How Close Are We to the Target?
  4. Evaluation of HBeAg-Negative Chronic Hepatitis B Patients Who Had Undergone Liver Biopsy in Accordance With the Guidelines
  5. Diagnosis, Treatment and Prevention of Diabetic Foot Wounds and Infections: Turkish Consensus Report
  6. When to Stop Antiviral Therapy in Chronic Hepatitis B
  7. Mycoplasma hominis and Ureaplasma urealyticum: Their Role in Urogenital System Infections and Retrospective Evaluation of Antibiotic Resistance Rates
  8. Crimean-Congo Haemorrhagic Fever: Treatment and Use of Ribavirin
  9. Modern Diagnostic Methods Used in Bacteriology: Rapid and Effective
  10. A Case of Generalized Tetanus With a Short Incubation Period
  11. Analysis of HIV/AIDS-Related Stigma and Discrimination in Turkey: Results of the People Living With HIV Stigma Index
  12. Does Anti-HIV Positivity in Pregnancy Suggest the Requirement of HIV Prophylaxis for Newborn?

Volume 33, Issue 1

Original Article

Antibiotic Resistance Pattern in Significant Bacteriuria: What Is the Current Situation in the Pediatric Nephrology Department?

Sibel Yel
Affiliations
  • Erciyes Üniversitesi, Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Çocuk Nefroloji Bilim Dalı, Kayseri, Türkiye
,
Ayşe Seda Pınarbaşı
Affiliations
  • Erciyes Üniversitesi, Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Çocuk Nefroloji Bilim Dalı, Kayseri, Türkiye
,
Pınar Sağıroğlu
Affiliations
  • Erciyes Üniversitesi, Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Kayseri, Türkiye
,
Mustafa Altay Atalay
Affiliations
  • Erciyes Üniversitesi, Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Kayseri, Türkiye
,
Funda İpekten
Affiliations
  • Erciyes Üniversitesi, Tıp Fakültesi, Biyoistatistik Anabilim Dalı, Kayseri, Türkiye
,
İsmail Dursun
Affiliations
  • Erciyes Üniversitesi, Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Çocuk Nefroloji Bilim Dalı, Kayseri, Türkiye
  • childhood
  • microbial drug resistance
  • Urinary tract infections

Objective: In order to contribute the empirical treatment of urinary tract infections in children, the antibiotic resistance patterns of uropathogens isolated in one center over a year, and clinical risk factors were evaluated in this study.

Methods: In this single-center study, the positive urine cultures and their antibiotic susceptibilities in a Child Nephrology Outpatient Clinic between March 2018 and March 2019 were evaluated retrospectively. Patient records, demographic data, obtaining method of urine and accompanying urinary tract problems were noted. Antibiotic susceptibility testing results of patients with significant bacteriuria were evaluated. Multidrug resistant (MDR) organisms were described as having resistance to at least three different groups of antimicrobials. Independent clinical risk factors were investigated by logistic regression analysis in infections due to MDR organisms.

Results: The most common two organisms were Escherichia coli (74.3%) and Klebsiella spp. (10.6%). Resistance rates to cefuroxime and trimethoprim-sulfamethoxazole (TMP-SXT) was 40.6% and 44% for E. coli, and 60.8% and 63% for Klebsiella spp. respectively (p<0.05). Extended spectrum β-lactamase (ESBL) positivity rate was 25.6% among all bacterial isolates. MDR isolates were detected in 63.8% of ESBL-positive organisms whereas it was 36.2% in ESBL-negative ones. Male gender rate was 31.9% in infections due to MDR pathogens, and 20.1% in infections with susceptible ones (p<0.05). Neurogenic bladder and male gender were determined as independent risk factors for isolation of MDR pathogens.

Conclusions: It must be taken into consideration that there is a high resistance to cephalosporins and TMP-SXT in the significant bacteriuria of children with accompanying urinary tract disorders. MDR pathogens are an increasing problem in these patients especially in boys.

Klimik Dergisi 2020; 33(1): 77-81.

Cite this article as: Yel S, Pınarbaşı AS, Pınar Sağıroğlu P, Atalay MA, İpekten F, Dursun İ. [Antibiotic resistance pattern in significant bacteriuria: What is the current situation in the Pediatric Nephrology Department?]. Klimik Derg. 2020; 33(1): 77-81. Turkish.

  • 77-81
  • 10.5152/kd.2020.15
  • April 29, 2020
  • 1650
  • 550
Download as PDF
  • This work is licensed under a Creative Commons Attribution-Non Commercial 4.0 International License. CC BY-NC
Volume 37, Issue 3 Volume 37, Issue 2 Volume 37, Issue 1 Volume 36, Issue 4 Volume 36, Supplement 1 Volume 36, Issue 3 Volume 36, Issue 2 Volume 36, Issue 1 Volume 35, Issue 4 Volume 35, Issue 3 Volume 35, Issue 2 Volume 35, Issue 1 Volume 34, Issue 3 Volume 34, Issue 2 Volume 34, Issue 1 Volume 33, Issue 3 Volume 33, Issue 2 Volume 33, Issue 1 Volume 32, Issue 3 Volume 32, Supplement 1 Volume 32, Supplement 2 Volume 32, Issue 2 Volume 32, Issue 1 Volume 31, Issue 3 Volume 31, Issue 2 Volume 31, Supplement 1 Volume 31, Issue 1 Volume 30, Issue 3 Volume 30, Issue 2 Volume 30, Supplement 1 Volume 30, Issue 1 Volume 29, Issue 3 Volume 29, Issue 2 Volume 29, Issue 1 Volume 28, Supplement 1 Volume 28, Issue 3 Volume 28, Issue 2 Volume 28, Issue 1 Volume 27, Supplement 1 Volume 27, Issue 3 Volume 27, Issue 2 Volume 27, Issue 1 Volume 26, Issue 3 Volume 26, Supplement 1 Volume 26, Issue 2 Volume 26, Issue 1 Volume 25, Issue 3 Volume 25, Issue 2 Volume 25, Issue 1 Volume 24, Issue 3 Volume 24, Issue 2 Volume 24, Issue 1 Volume 23, Issue 3 Volume 23, Issue 2 Volume 23, Issue 1 Volume 22, Issue 3 Volume 22, Issue 2 Volume 22, Issue 1 Volume 21, Issue 3 Volume 21, Supplement 2 Volume 21, Supplement 1 Volume 21, Issue 2 Volume 21, Issue 1 Volume 20, Issue 3 Volume 20, Supplement 2 Volume 20, Issue 2 Volume 20, Issue 1 Volume 20, Supplement 1 Volume 19, Issue 3 Volume 19, Issue 2 Volume 19, Issue 1 Volume 18, Issue 3 Volume 18, Supplement 1 Volume 18, Issue 2 Volume 18, Issue 1 Volume 17, Issue 3 Volume 17, Issue 2 Volume 17, Issue 1 Volume 16, Issue 3 Volume 16, Issue 2 Volume 16, Issue 1 Volume 1, Supplement 1 Volume 15, Issue 3 Volume 15, Issue 2 Volume 15, Issue 1 Volume 14, Issue 3 Volume 14, Issue 2 Volume 14, Issue 1 Volume 13, Issue 3 Volume 13, Issue 2 Volume 13, Supplement 1 Volume 13, Issue 1 Volume 12, Issue 3 Volume 12, Issue 2 Volume 12, Issue 1 Volume 11, Issue 3 Volume 11, Issue 2 Volume 11, Supplement 1 Volume 11, Issue 1 Volume 10, Issue 3 Volume 10, Issue 2 Volume 10, Issue 1 Volume 9, Issue 3 Volume 9, Issue 2 Volume 9, Issue 1 Volume 8, Issue 3 Volume 8, Issue 2 Volume 8, Issue 1 Volume 6, Issue 3 Volume 7, Issue 1 Volume 7, Issue 2 Volume 7, Issue 3 Volume 4, Issue 3 Volume 5, Issue 1 Volume 5, Issue 2 Volume 5, Issue 3 Volume 6, Issue 1 Volume 6, Issue 2 Volume 3, Issue 1 Volume 3, Issue 2 Volume 3, Issue 3 Volume 4, Issue 1 Volume 4, Issue 2 Volume 1, Issue 2 Volume 2, Issue 1 Volume 2, Issue 2 Volume 2, Issue 3 Volume 1, Issue 1