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Volume 23, Issue 2

Original Article

Levels of Acute Phase Reactants in Patients with Acute Brucellosis

Mehmet Uluğ
Affiliations
  • Özel BSK Anadolu Hastanesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Kliniği, Kütahya, Türkiye
,
Nuray Can-Uluğ
Affiliations
  • Özel Ümit Hastanesi, Nöroloji Kliniği, Eskişehir, Türkiye
,
Şehabettin Selek
Affiliations
  • Kafkas Üniversitesi, Tıp Fakültesi, Biyokimya Anabilim Dalı, Kars, Türkiye
  • acute phase reactants
  • Brocellosis
  • Creactive protein
  • ferritin

Abstract

Objective: Infection, tissue damage, immunologic reactions and the inflammatory process rapidly cause a systemic response in the organism, generally termed as acute phase response. The aim of this study was to evaluate the levels of acute phase reactants such as C-reactive protein (CRP), ferritin and fibrinogen in patients with acute brucellosis.

Methods: This study was carried out in 48 patients (27 female, 21 male) with acute brucellosis who were followed at the Departments of Infectious Diseases and Neurology, between April 2007 and August 2008, and in 42 healthy controls (22 female, 20 male).

Results: Serum albumin levels significantly decreased (p<0.001), whereas CRP and ferritin levels significantly increased (p<0.001 and p=0.03) in patients with acute brucellosis.

Conclusions: It was concluded that serum levels of CRP and ferritin increased, while albumin decreased in patients with acute brucellosis

  • 48-50
  • 10.5152/kd.2010.15
  • July 23, 2019
  • 2339
  • 747
Download as PDF
  • This work is licensed under a Creative Commons Attribution-Non Commercial 4.0 International License. CC BY-NC
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