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Volume 22, Issue 3

Original Article

Quick Test “Problem” in Diagnosis of Pandemic A/H1N1 Infections

Melis Kanturvardar
Affiliations
  • İstanbul Üniversitesi, İstanbul Tıp Fakültesi, Viroloji ve Temel İmmünoloji Bilim Dalı, Ulusal İnfl uenza Referans Laboratuvarı, İstanbul, Türkiye
,
Meral Akçay-Ciblak
Affiliations
  • İstanbul Üniversitesi, İstanbul Tıp Fakültesi, Viroloji ve Temel İmmünoloji Bilim Dalı, Ulusal İnfl uenza Referans Laboratuvarı, İstanbul, Türkiye
,
Serkan Asar
Affiliations
  • İstanbul Üniversitesi, İstanbul Tıp Fakültesi, Viroloji ve Temel İmmünoloji Bilim Dalı, Ulusal İnfl uenza Referans Laboratuvarı, İstanbul, Türkiye
,
Emel Bozkaya
Affiliations
  • İstanbul Üniversitesi, İstanbul Tıp Fakültesi, Viroloji ve Temel İmmünoloji Bilim Dalı, Ulusal İnfl uenza Referans Laboratuvarı, İstanbul, Türkiye
,
O. Şadi Yenen
Affiliations
  • İstanbul Üniversitesi, İstanbul Tıp Fakültesi, Viroloji ve Temel İmmünoloji Bilim Dalı, Ulusal İnfl uenza Referans Laboratuvarı, İstanbul, Türkiye
,
Selim Badur
Affiliations
  • İstanbul Üniversitesi, İstanbul Tıp Fakültesi, Viroloji ve Temel İmmünoloji Bilim Dalı, Ulusal İnfl uenza Referans Laboratuvarı, İstanbul, Türkiye
  • Pandemic AH1N1
  • quick test
  • RTPCR

Abstract

Objective: Real-time RT-PCR has been used as  reference technique for the detection of pandemic A/H1N1 influenza virus infections. In addition, rapid antigen detection tests such as quick tests have been considered in the diagnosis of pandemic A/H1N1 worldwide due to their ease of use and generation of  rapid  results. These tests have been used by numerous institutions for the diagnosis of pandemic A/H1N1 in Turkey also. The aim of this study is to compare the sensitivity of quick tests with the  reference method.

Methods: A total of 104 positive isolates by real time RT-PCR technique has been tested with four quick tests manufactured by different companies marketed in our country.

Results: The sensitivity of quick tests ranged from 31.7% to 50% in detecting pandemic A/H1N1 infections.

Conclusions: Based on the results of this study, it can be concluded that quick tests are not adequately sensitive in the detection of pandemic A/H1N1 infections.

  • 79-81
  • July 23, 2019
  • 1941
  • 677
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  • This work is licensed under a Creative Commons Attribution-Non Commercial 4.0 International License. CC BY-NC
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