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Volume 35, Issue 4

Original Article

Evaluation of Tetanus Seropositivity in Healthcare Professionals by Age and Occupational Groups

Gülsüm Çam
Affiliations
  • Sağlık Bilimleri Üniversitesi Ümraniye Eğitim ve Araştırma Hastanesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Kliniği, İstanbul, Türkiye
https://orcid.org/0000-0002-9776-8475
,
Ayşe Serra Özel
Affiliations
  • Sağlık Bilimleri Üniversitesi Ümraniye Eğitim ve Araştırma Hastanesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Kliniği, İstanbul, Türkiye
https://orcid.org/0000-0003-2111-1183
,
Ayten Kadanalı
Affiliations
  • Biruni Üniversitesi Tıp Fakültesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, İstanbul, Türkiye
https://orcid.org/0000-0002-3176-2126
  • adult vaccination
  • healthcare workers
  • tetanus seropositivity
  • vaccine-preventable disease

Abstract

Objective: Our country has limited data on protective antibody levels following primary tetanus immunization. In this study, we planned to evaluate the tetanus antibody seroprevalence of healthcare workers in our hospital according to age and occupational groups.

Methods: Tetanus antibody levels were determined by the enzyme-linked immunosorbent assay (ELISA) method. Antibody results were obtained through the hospital operating system, and the tetanus antibody level ≥0.5 IU/mL was considered seropositive.

Results: 77.5% of 2082 healthcare workers were seropositive. According to age groups, the highest seropositivity was between 20-29; the lowest seropositivity was found in individuals over 50 years of age and over (66.3%). We determined that tetanus antibody protection decreased with age (p=0.03). There was no difference between tetanus seropositivity according to occupational groups.

Conclusion: Antibody levels of tetanus decrease with age, and protection decreases significantly, especially over 50 years of age. It is important to apply a booster dose every ten years following the primary vaccine schedule in tetanus immunization.

  • 249-52
  • Ayşe Serra Özel
  • [email protected]
  • 10.36519/kd.2022.4191
  • January 24, 2022
  • July 23, 2022
  • November 17, 2022

  • Çam G, Özel AS, Kadanalı A. [Evaluation of tetanus seropositivity in healthcare professionals by age and occupational groups]. Klimik Derg. 2022;35(4):249-52. Turkish.

  • 482
  • 489
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  • This work is licensed under a Creative Commons Attribution-Non Commercial 4.0 International License. CC BY-NC
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